Genetics Close to Solving the World’s Deadliest Problem

Genetic engineering and gene editing applications may enable the treatment of many diseases in the future. A promising development has been announced from New Zealand in this regard.

Gene therapy and gene editing studies very promising Although they have potential, ethical debates on the subject continue. Despite all the turmoil in the field, positive news continues to come from geneticists.

New ZelandA volunteer in Turkey to fight high cholesterol first person to accept self-editing of DNA it happened. This study is also important in terms of showing how gene-editing technology may have future effects.

It was a first in history

USA based Verve Therapeutics In the study, the volunteer’s liver was injected with the gene editing tool CRISPR and a single letter in his DNA was changed. Thus, the gene that causes cholesterol has been edited.

According to the firm, this simple arrangement “bad cholesterol” also known as LDL cholesterol It will help it fall permanently. LDL cholesterol is a fat molecule in the blood and can sometimes cause clogged arteries or hardening of the arteries.

The volunteer participating in the study is already genetically extra risk of high cholesterol It was stated that he also suffered from a heart disease. According to the company, this technique cardiovascular It can be used in millions of people to prevent ailments.

Founder of Verve 3 years ago and also assumed the CEO position of the company. Sekar Kathiresan, “If this works and is safe, that will be the answer to the heart attack—that’s the cure.10 years ago despite the development If CRISPR, which is used only for rare chronic conditions, turns out to be effective and safe, a new step can be taken in the fight against uncontrollable genetic disorders. In the gene editing study called PCSK9, it is predicted that if Verve is successful, cardiovascular diseases, which are the biggest cause of death, can be prevented. Moreover, there is no need to spend hundreds of thousands of dollars in this method.

RELATED NEWS

A Small Part of the Human Heart Was Developed From Scratch in the Lab (And It Beats)

Source :
https://www.technologyreview.com/2022/07/12/1055773/crispr-gene-editing-cholesterol/


source site-34