While the location of our organs is clear, this is not the case for some people. In people with this genetic disorder, the organs are on the opposite side of where they should be. The problem, which most of the time does not cause any problems unless examined with examinations such as imaging devices, can manifest itself differently in different species.
In medicine, “situs inversus totalis” This condition, called ‘reversal’, is a rare condition characterized by the reverse change of the organs in their mirror images. congenital anomaly is shown as .
“Does the fact that the organs are upside down affect the person’s life negatively? Isn’t it possible to understand?We searched for answers to some curious questions such as.
All organs may be on the opposite side, sometimes only the heart is in the right direction and the others may be displaced.
Our body externally symmetrical While it has an appearance, the same does not apply to internal organs. Generally speaking, every organ has its place. However, this works the opposite for some people.
A-Situs Solitus B-Situs Inversus Totalis
According to the change in organs, the name of the genetic disorder is situs inversus, which simply means that the internal organs have a mirror appearance. Situs inversus totalis (SIT) is that the heart as well as the internal organs are in an upside down position. I mean dextrocardia right-heartedness The heart is in the right chest, not the left.
From left head: Normal appearance of organs – Change in the Axis of the Heart Only – Mirror view of all organs
There is also situs ambiguus or heterotaxy. This indicates that the exact location of the organs is not clear. While the liver can be found in the middle There may be no spleen or there may be more than one.
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Doesn’t it cause any symptoms if the organs are not in their normal place?
Abdominal imaging with right-sided spleen and left-sided liver noted
In situs inversus, that is, the organs being on the opposite side, individuals usually There are no medical symptoms or complications. In fact, this situation was not noticed until the development of modern medicine.
Since there may be risky situations when the internal organs are reversed and the heart is normal, people He may need surgery. Patients whose organ location is unclear are more likely to encounter medical problems than SIT patients.
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How does the location of organs change?
Situs inversus is inherited through autosomal recessive inheritance
Although the cause of this situation is not fully known, mutations in the nodal and PITX2 genes, which play an active role in the developmental process, are also responsible for determining the right-left asymmetry during development. multiple gene mutations is associated with. Primary ciliary dyskinesia Some disorders such as are also linked to this disease.
While our body is symmetrical from the outside, why are the location and shape of our internal organs not symmetrical?
Displacement of organs was first described by Aristotle.
Mirror image positioning of the heart and lungs
This anomaly situation was first discovered by Aristotle, identified in animals. It was first observed in humans in the 17th century. The first known case of reversal of the spleen and liver dates back to the year 1600. The first case of heart reversal was reported in 1643.
There are some difficulties in the diagnosis and treatment of situs inversus totalis.
Diagnosis may be difficult in patients’ emergency situations. Therefore, the patient must be aware of his/her situation and this must be recorded. Otherwise, in addition to the blockage of the heart vessels, some serious situations may occur.
Some patients believe that this disorder does not pose a problem in emergency situations and require correct intervention. tattoo on their body It looks like he had it done.
Frequency of situs inversus 1 in 10 thousand and is more common in men. Its rarity; It also causes difficulties for some doctors such as radiologists, gastroenterologists and surgeons. Doctors about patients He doesn’t have much experience. Even the busiest surgeon may encounter this anomaly once or twice.
Most The surgeon is right-handed, It is among the situations that make SIT surgeries challenging. Therefore, the surgical team needs more flexibility and creativity.
There are also cases that occur in different ways.
Some cases were also reported in the news in Turkey. However, there are people with this disorder in the world. interesting cases There is also. What makes the situation interesting is the age at which it was learned and the situation that caused the incident.
One of the artists that everyone knows Enrique Iglesias is coming. Writer and comedian Catherine O-Hara as well as NBA player Randy Foye is among these names. In fact, this situation does not affect Randy Foye’s athletic life.
Ginggaew Lorsoungnern, on the other hand, saved him from death for the first time because his organs were inverted. Thai criminal executed by firing squad is shot in the left side of his chest. waking up in the morgue Lorsoungnern is taken back and executed.
Rose Marie Bentley from the USA lived until the age of 99 without knowing that her organs were reversed. Upon noticing the abnormal location of the vessels in the heart, body as a cadaver It is being donated to Oregon Health and Science University.
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