A company called LyGenesis has started to test the liver failure treatment it has been developing for more than 10 years on humans for the first time. The treatment can turn lymph nodes into livers.
Scientists are constantly trying to develop treatments for diseases that can have fatal consequences. A method that has been studied for more than ten years and involves lymph nodes is one of them. This treatment aims to solve end-stage liver diseases. Now there has been a very important development regarding this treatment. Developer company LyGenesis announced that the first human experiment has officially started.
The method developed by LyGenesis turns lymph nodes into liver. This is from a donated liver by taking healthy cells and injecting them into the lymph nodes It’s happening. The cells are filtered and transferred to the lymph nodes to remove things like viruses that cause infection. After this, the cells in the glands need to grow, divide and connect to the circulatory system. Eventually, the lymph node disappears. a miniature organ it’s coming out.
Treatment aims to solve diseases by transforming lymph nodes into liver
The procedure had actually been tested on animals for some time. pigs Successful results were seen in the experiments carried out on it. The researchers surgically modified pig livers to mimic human liver disease and transplanted healthy liver samples into lymph nodes. As a result of these mini livers added to the 6 pigs in the experiment, signs of improvement in liver failure was seen.
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Now, human experiments have officially begun. The company’s co-founder and CEO, Dr. Michael Hufford in a clinical trial They dosed the first patient announced and announced that they had broken new ground.
The effects of this cell therapy on safety and efficiency will be observed in human trials involving up to 12 people. All of these patients have end-stage liver disease. At this stage, the liver is in a condition that cannot be repaired and organ transplantation is often required. However, even this does not happen because some patients are unable to undergo surgery.
It can also eliminate the problem of organ transplantation
The new treatment also has the potential to solve the problem of waiting for a transplant. Nowadays, the number of people waiting for a liver transplant is quite high. For example, in the USA, 10,000 people are waiting for donations and the waiting period for donations is up to 5 years can come out. According to estimates, 12% of these people are likely to die each year. LyGenesis says that once it gets approval from agencies like the US Drug Administration and is successful in trials, it could treat dozens of patients with a single liver and eliminate the problem of transplants.
We have to wait a bit to see the results of human experiments. Researchers will follow the patients for 1 year. The most appropriate dose, reliability and suitability of the treatment will be checked. We hope there will be successful results.
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