Leber’s Congenital Amaurosis Could Be Completely History!

There has been an important development regarding Leber’s congenital amaurosis, also known as genetic blindness. Scientists have found that the methods applied in infancy also give results in adults. Research can bring the end of LCA disease.

serving in the USA University of California The scientists who continue their work in the company conducted a remarkable research on “genetic blindness” called leber congenital amaurosis (LCA). As a result of the researches, it is seen that retinoid treatment applied in infancy can also be applied in adult individuals. it might work understood. Experts say this research means that blindness untreated in infancy can be treated in adulthood.

LCA is an inherited disease transmitted through genes. a retinal caused by a gene defect The disease manifests itself as little or no vision during infancy. If left untreated, it can lead to permanent blindness. Here, the latest research has revealed that the techniques applied for LCA are not only specific to infancy. This condition is blind to people There may be a new hope.

It is not yet clear how effective the research is

Scientists working on adult mice adapted the treatment method applied in infancy to adults. To eye synthetic ingredients Injecting specialists continued this process for a week. Examining the behavior of the mice for 27 days after the treatment was completed, the experts started seeing results by the ninth day after the treatment. Adult mice with genetic blindness they began to react to light. Sunil Gandhi of the University of California states that the findings are surprisingly good. So much so that the activity of the nerves that enable the mice to see is doubled in the first stage and after a while after the treatment. increased 5 times.

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Although the research is promising, it has important shortcomings. Such that the visual acuity of the treated mice at what level not fully known. Experts are now chasing this issue. As a result of the studies to be done, if it is determined how much the mice can see, the scope of the research can be expanded and tests on humans can also start.

Source :
https://www.sciencedirect.com/science/article/pii/S096098222201449X?via%3Dihub


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