Antibiotics and Cognitive Decline May Be Linked

The relationship between the gut microbiome and the brain has been linked to many previous studies. a link It is underlined that; however, there was no clear explanation as to the exact nature of this relationship. In a recent study on the subject, New informations obtained.

In the new study, published in PLOS One, of a total of 14,542 women, midlife for two months. during a period of antibiotic use and cognitive score evaluations a few years later. drop A link was found between What exactly this connection is still remains a mystery.

Long-term antibiotic exposure may cause cognitive impairment

In the study, led by epidemiologists from Harvard Medical School in Massachusetts, participants’ cognitive ability was assessed with an online test that participants took at home an average of seven years after the start of antibiotic use, and participants did not participate in this test. different aspects of cognitive performance It was subjected to a total of four different tasks designed to measure

In the research article “In a group of more than 14,000 women, midlife antibiotic use was associated with later lower scores for global cognition, learning and working memory, and psychomotor speed and attention. significantly related We observed that ” researchers, who stated “To the best of our knowledge, our study focuses on chronic long-term antibiotic use and subsequent cognition. first major work represents.” conveyed in the form. However, the team continued their work in terms of carefully monitoring antibiotic use, as well as understanding the link between what’s going on in our gut and brain and which antibiotics are affecting this condition. quite important noted that.

As a result of the research, women who took antibiotic drugs for various reasons, including respiratory tract infections, dental problems, acne and urinary tract infections. long-term use of antibiotics in various learning, response and memory categories decline in brain powerapproximately three or four years into normal aging equivalent was detected. On the subject, researchers “This association was associated with longer duration of antibiotic use and persisted after adjusting for many possible confounding factors.” expressed as.

However, as always in such studies, this connection does not show a cause-effect relationship. prove It should be noted that this is not sufficient. That is, the data obtained do not conclusively prove that it is the use of antibiotics that causes the decline in cognition.

On the other hand, this research provides conclusive evidence that more research on the subject is needed. Researchers related to this “Given the profound impact of antibiotic use on the gut microbiome, as evidenced by previous studies showing changes in functional potency two and four years after antibiotic exposure, the gut-brain axis is needed to correlate antibiotics with cognitive function. a possible mechanism it could be” states as.