Scientists from the Salk Institute in the USA managed to reverse the effects of aging in their study on mice. The cells of the mice exposed to a treatment method literally time-traveled.
The aging of every living thing over time eventually causes the living thing to die due to natural causes resulting from aging. But science has been around for a very long time. a method to prevent aging trying to find. Scientists from the Salk Institute in the USA broke new ground in history with their newly published work.
Using the genes OCT4, SOX2, KLF4 and MYC, known as “Yamanaka factors”, scientists were able to modify the cells of mice. Thanks to this change, the cells of the mice became younger than they were. That is, cells as if traveling in time rejuvenated.
The world of science has succeeded in slowing down aging
As part of the study, the scientists tested variations of the cellular rejuvenation approach on healthy mice as they age. Mice aged 15 months to 22 months, or 50 to 70 years old when converted to human age, were given regular doses of Yamanaka factors. Mice 12 – 22 months old (35 – 70 human years old) were then given the same treatment for only one month in a group of 25 months old (80+) mice.
As a result of the tests, scientists determined that the animals treated kidney and skin patterns He saw that it began to resemble young mouse individuals in tissues such as However, test subjects’ cells regenerated faster when injured. Their body’s metabolic molecules also showed no age-related changes.
But tests also showed something else. This treatment, which appears to inhibit aging, only worked in mice that were regularly injected with Yamanaka factors over long periods of time. No similar effect was seen in mice treated for one month, such as mice older than 25 months of age. The scientists will therefore now analyze prospectively how long-term treatment plans change certain molecules.
Source :
https://designtaxi.com/news/418045/Scientists-Hit-Breakthrough-By-Reversing-Signs-Of-Aging-In-Mice/